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目的:观察坤安煎剂对去卵巢大鼠血清甘油三酯(TG)、胆固醇(TC)水平的影响。方法:将52只雌性大鼠随机分为空白组、模型组、补佳乐组、中药组4组。除空白组外,其余各组大鼠均摘除双侧卵巢模拟更年期卵巢功能衰退的模型,给予不同药物灌8周后,观察各组大鼠血清甘油三酯(TG)、胆固醇(TC)水平的变化。结果:同空白组相比,去卵巢大鼠TG、TC水平显著升高,在益肾填精中药“坤安煎剂”干预后大鼠TG、TC值有下降趋势(P<0.05)。结论:“坤安煎剂”可明显调节去卵巢大鼠的血脂水平。
Objective: To observe the effect of Kunan decoction on serum triglyceride (TG) and cholesterol (TC) in ovariectomized rats. Methods: Fifty-two female rats were randomly divided into four groups: blank group, model group, bujiale group and traditional Chinese medicine group. Except for the blank group, all the rats in the other groups were enrolled in this study. Both ovaries were ovariectomized to model ovarian failure in menopause. After being given different drugs for 8 weeks, the levels of serum triglyceride (TG), cholesterol (TC) Variety. Results: Compared with the blank group, the levels of TG and TC in ovariectomized rats were significantly increased. The TG and TC values of the rats after the intervention of Yishenhenjiejing injection and “Kunan Decoction” decreased gradually (P <0.05) . Conclusion: “Kuan An decoction” can obviously regulate blood lipid level in ovariectomized rats.