1993年至1995年间,我院对消化溃疡病急性大出血15例病人,经常规H_2受体阻滞剂和质子泵拮抗剂治疗,以及胃镜下止血治疗后3～5天仍出血不止者,应用生长抑素施他宁治疗。止血成功率为86.67％(13/15),2例出现再出血,经反复应用生长抑素后止血成功。本人认为对年老体弱,有重要脏器疾患者,出血量大,手术高危以及常规治疗无效者,应积极应用生长抑素治疗。 Between 1993 and 1995, 15 cases of acute bleeding caused by peptic ulcer disease were treated in our hospital by conventional H 2 blockers and proton pump antagonists. Hemorrhage more than 3 ~ 5 days after endoscopic treatment was stopped. Strychnine treatment. The success rate of hemostasis was 86.67% (13/15). Two cases had rebleeding, and the hemostasis was successful after repeated application of somatostatin. I think the elderly frail, important organ disease, bleeding, high risk of surgery and routine treatment ineffective, should be actively applied somatostatin treatment.