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更年期或围绝经期一般发生于45～47岁妇女，是妇女一生中的一个生理过程。但随之而来的还有病理变化，引起各种症状并导致疾病，如骨质疏松症和心血管疾病等。这些都与体内雌激素水平下降有关。单就人体内雌激素水平下降引起的骨质疏松症，国内目前多采用激素替代疗法（HRT）。
Menopause or perimenopausal women generally occur in 45 to 47-year-old women, women’s life is a physiological process. But then there are pathological changes that cause a variety of symptoms and lead to diseases such as osteoporosis and cardiovascular disease. These are related to the decline of estrogen levels in the body. Osteoporosis alone caused by the decline of estrogen in the human body, the domestic use of hormone replacement therapy (HRT).