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目的:回顾性分析四川省巴中市中心医院10年间收治的153例白血病患儿的临床资料,探讨本地区儿童白血病的分布规律及流行病学特征。方法:对2007年1月至2016年8月就诊于我院的153例初诊白血病患儿的临床资料进行回顾性分析。结果:153例白血病患儿的男女性别比1.64∶1;其中急性淋巴细胞白血病(Acute Lymphoblastic Leukemia,ALL)和急性髓细胞白血病(Acute Myeloid Leukemia,AML)患儿的男女性别比分别为1.82∶1和1.79∶l。儿童白血病的发病高峰年龄为1~9岁,占73.2%(112/153),110例ALL患儿的发病高峰为1~4岁,共47例(42.7%),AML无明显发病年龄高峰。春夏秋冬四季白血病患儿分别有42例(27.5%)、39例(25.5%)、35例(22.9%)和37例(24.2%),ALL春冬季发病例数较多,而AML则为夏秋季发病例数较多。10年间四川省巴中市中心医院收治的儿童白血病初诊患者呈动态上升趋势,平均年增长率为15.8%。结论:不同性别、年龄、季节、年代儿童白血病发病存在差异,白血病各亚型发病率不一。
OBJECTIVE: To retrospectively analyze the clinical data of 153 leukemia children admitted to Central Hospital of Bazhong in Sichuan Province for 10 years to investigate the distribution and epidemiological characteristics of childhood leukemia in this area. Methods: The clinical data of 153 newly diagnosed leukemia patients treated in our hospital from January 2007 to August 2016 were analyzed retrospectively. Results: The odds ratio of male to female in 153 children with leukemia was 1.64:1. The male to female sex ratio of children with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) were 1.82:1 And 1.79: l. The onset age of childhood leukemia was from 1 to 9 years old, accounting for 73.2% (112/153). The incidence of childhood ALL was 1 to 4 years old, with a total of 47 cases (42.7%). There was no significant age at onset of AML. There were 42 (27.5%), 39 (25.5%), 35 (22.9%) and 37 (24.2%) children with leukemia in the seasons of spring, summer, The incidence of summer and autumn more cases. The newly diagnosed childhood leukemia patients admitted to Central Hospital of Bazhong in 10 years showed a dynamic upward trend with an average annual growth rate of 15.8%. Conclusion: There are differences in the incidence of leukemia among children of different genders, ages, seasons and ages, and the incidence of leukemia subtypes is different.