在子宫癌中体癌的比例逐渐增加,至今一直认为子宫内膜癌的发生和发展,与雌激素过多或内分泌失调有关。对绝经后导致子宫内膜癌患者雌激素过多的因子中,以内源性及外源性雌酮引人注目。关于内源性雌酮的来源,由于子宫内膜癌患者75%发生于绝经后,故对该年龄组的内分泌环境,特别是雌激素的来源作了探讨。 Longcope和Gordin指出,绝经妇女的雌激素是雄激素通过末梢器官转变(基本上是从雄甾烯 The proportion of body cancer in uterine cancer gradually increased, has been that the occurrence and development of endometrial cancer, and estrogen or endocrine disorders. Of postmenopausal women lead to endometrial estrogen excess factor, with endogenous and exogenous estrone attention. As for the source of endogenous estrone, since 75% of endometrial cancer patients occur after menopause, the endocrine environment of this age group, especially the source of estrogen, is discussed. Longcope and Gordin point out that the estrogen in menopausal women is a form of androgens that is transformed by terminal organs (essentially from androstene