自发性急进性肾小球肾炎的特征是新月体形成及肾功能迅速恶化。由于抗凝剂、类固醇、细胞毒药物无显著疗效,大多数病人需要血液透析(下称血透)。本文叙述3例自发性急逃性肾小球肾炎病人,血透后无任何特异性治疗,自行痊愈。急进性肾小球肾炎可分为3种不同的免疫荧光类型:Ⅰ型显示弥漫线状 IgG 染色,合并抗肾小球基膜抗体;Ⅱ型显示弥漫粒状 IgG、IgM 沉积,较少出现 IgA 沉积,伴有 C3沉积于外周毛细血管袢;Ⅲ型显示稀少 IgG 或 C3沉积,或无沉积。本组病人属免疫荧光Ⅲ型。所有病人于数月血透后未接受特异性治疗而痊愈。当然不能排除血透时使用肝素的良好效果。作者发现具Ⅲ型病人比具Ⅰ、Ⅱ型病人有较良性病程。在 Bolton 和 Couser 的病例 Spontaneous aggressive glomerulonephritis is characterized by crescent formation and rapid deterioration of renal function. Because of anticoagulants, steroids, cytotoxic drugs no significant effect, most patients need hemodialysis (hereinafter referred to hemodialysis). This article describes three patients with spontaneous escape of glomerulonephritis, hemodialysis without any specific treatment, self-healing. Acute progressive glomerulonephritis can be divided into three different types of immunofluorescence: type I showed diffuse linear IgG staining, combined anti-glomerular basement membrane antibodies; type II showed diffuse granular IgG, IgM deposition, less deposition of IgA , Accompanied by the deposition of C3 in peripheral capillaries; type III showed rare IgG or C3 deposition, or no deposition. This group of patients are immunofluorescence type Ⅲ. All patients recovered after several months of hemodialysis without specific treatment. Of course, can not rule out the hemodialysis when using heparin good effect. The authors found that patients with type Ⅲ than type Ⅰ, Ⅱ patients have a more benign course. Cases in Bolton and Couser