论文部分内容阅读
载药角膜接触镜(DCL)除视力矫正功能外,还可用于治疗诸如角膜炎、眼部过敏性疾病和白内障术后等眼科疾病,可替代眼药水给药带来给药效率低、患者不适和反复给药等问题。DCL可显著提高给药效率和药物缓释时间,具有广泛的眼科临床应用前景。笔者就DCL的发展、载药模式和缓释模式等做综述,为今后设计新型DCL及在临床应用提供可供参考的资料。
In addition to the vision correction function, drug-loaded contact lens (DCL) can be used to treat ophthalmic diseases such as keratitis, allergic eye diseases and post-cataract surgery, and can be used in place of ophthalmic solution to deliver drugs with low efficiency and patient discomfort And repeated administration and other issues. DCL can significantly improve the drug delivery efficiency and drug release time, with a wide range of ophthalmic clinical application prospects. The author summarizes the development of DCL, drug-loading mode and sustained-release mode, and provides a reference for the future design of new DCL and clinical application.