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目的 长期随访SARS后遗症-肺纤维化的变化,观察预后。方法 分别于SARS患者发病后6、9、12个月,采用螺旋CT行胸部扫描随访检查SARS康复人员肺纤维化变化。结果 6个月:5 6例患者中2 2例胸部CT显示局部磨玻璃和(或)网格状影,肺纤维化发生率39.2 9%。9个月:6 3例患者中2 2例胸部CT显示局部磨玻璃样或(和)网格状影,肺纤维化发生率34.92 %。12个月:74例患者中2 8例胸部CT显示局部磨玻璃样或(和)网格状影,肺纤维化发生率37.84 %。3组间比较无显著性差异( χ2 =0 .6 88,P >0 0 5 )。比较不同时间CT检查所见的侵及肺叶数目,随时间延长逐渐减少,3组之间差异显著( χ2 =5 .898,P <0 0 5 )。结论 1年随访结果表明SARS后遗症-肺纤维化病情稳定,并呈恢复减轻趋势
Objective Long-term follow-up of SARS sequelae - changes in pulmonary fibrosis, prognosis. Methods The changes of pulmonary fibrosis in SARS rehabilitation workers were detected by spiral CT at 6, 9 and 12 months after the onset of SARS. RESULTS: Six months: Twenty-two of 56 patients had locally ground glass and / or grid-like CT, and the incidence of pulmonary fibrosis was 39.2%. 9 months: Twenty-two of 36 patients with chest CT showed local ground glass or (or) grid-like appearance, and the incidence of pulmonary fibrosis was 34.92%. Twelve months: Twenty-eight of the 74 patients underwent chest CT scans showing a local ground-glass or (and) grid-like appearance with a pulmonary fibrosis rate of 37.84%. There was no significant difference between the three groups (χ2 = 0.688, P> 0.05). Comparing the number of invasion and lobes seen by CT at different time points, it gradually decreased with time, with significant difference between the three groups (χ2 = 5.988, P <0.05). Conclusions The results of 1-year follow-up showed that SARS sequelae-pulmonary fibrosis was stable and showed a trend of recovery and mitigation