论文部分内容阅读
现已阐明特异性免疫应答不仅需要T、B细胞上的抗原特异性受体的激活,而且还需要辅助分子间的抗原非依赖性相互作用。据认为,LFA-1能增强T细胞与抗原提呈细胞(APC)间的相互作用的亲和力,并参与跨越T细胞膜的信号转换。ICAM-
It has now been demonstrated that specific immune responses require not only the activation of antigen-specific receptors on T, B cells but also the antigen-independent interaction between accessory molecules. It is believed that LFA-1 enhances the affinity of T-cell interactions with antigen presenting cells (APCs) and is involved in signal transduction across T cell membranes. ICAM-