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目的:探讨慢性萎缩性胃炎(Chronic atrophic gastritis,CAG)应用铝碳酸镁混悬剂与胃炎I号联合方治疗的临床观察。方法:入组CAG患者62例,随机分为治疗组与对照组各31例,对照组给予铝碳酸镁混悬剂,治疗组给予铝碳酸镁混悬剂联合胃炎I号。比较两组临床疗效、症状改善情况。结果:(1)对照组与治疗组临床疗效分别为71.0%(44/62),89.1%(57/64),两组比较在统计学上具有显著性意义(x2=9.372,P<0.05)。(2)对照组与治疗组治疗后与同组治疗前比较,胃痛、纳差、嗳气、痞满积分均显著降低,在统计学上具有显著性意义;治疗后治疗组与对照组相比较,胃痛、纳差、嗳气、痞满积分均显著降低,在统计学上具有显著性意义(t=2.218,2.174,2.104,2.104;P<0.05)。结论:慢性萎缩性胃炎应用铝碳酸镁混悬剂与胃炎I号联合治疗,可以提高临床疗效,有效改善患者症状。
Objective: To investigate the clinical observation of Chronic atrophic gastritis (CAG) treated with combination of aluminum magnesium carbonate suspension and gastritis I. Methods: Sixty-two CAG patients were randomly divided into treatment group and control group with 31 cases each. The control group was given suspension of aluminum magnesium carbonate. The treatment group was given aluminum magnesium carbonate suspension combined with gastritis I. The clinical efficacy and symptom improvement were compared between the two groups. Results: (1) The clinical efficacy of the control group and the treatment group were 71.0% (44/62) and 89.1% (57/64), respectively, with statistical significance (x2 = 9.372, P <0.05) . (2) Compared with the same group before treatment, the scores of stomach ache, anorexia, belching and fullness in control group and treatment group were significantly decreased after treatment, which were statistically significant. After treatment, compared with control group, Stomach pain, anorexia, belching, fullness of the lumps were significantly reduced, statistically significant (t = 2.218,2.174,2.104,2.104; P <0.05). Conclusion: Chronic atrophic gastritis with aluminum magnesium carbonate suspension combined with gastritis I can improve clinical efficacy and effectively improve the symptoms of patients.