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作者根据Hurly报告乙氨嘧啶与磺胺嘧啶并用有显著的增效作用,对此进行了一些研究。研究的对象为171例間日瘧現症患者,分为6組,其中乙氨嘧啶100毫克合併磺胺嘧啶1克頓服或两日分服各一組;乙氨嘧啶100毫克頓服或两日分服各一組;乙氨嘧啶50毫克合併磺胺双甲基嘧啶1克頓服或連服两日各一组。治后第二、三、四、六天和第一、二月时各进行血检和訪問一次。治疗后各組平均退热时間为1.15～1.58天,平均为1.35天,其中治后不再发热者占57.7%～92.6%,平均为70.3%;瘧原虫平均在治后4天左右消
The authors have done some research on the synergistic effect of the combination of pyrimethamine and sulfadiazine reported by Hurly. The study object was 171 cases of P. vivax patients were divided into six groups, of which 100 mg of pyrimethamine sulfamethazine 1 克 Dayton service or two-day service of a group; 100 mg of pyrimethamine Dayton service or two-day service Each group; 50 mg of pyrimethamine with sulfamerazine double pyrimidine 1 克 Dayton served or even served one each for two days. After the second, third, fourth and sixth days and the first and second months of the month, blood tests and visits were conducted. After treatment, the average time for fever in each group was 1.15 ~ 1.58 days, with an average of 1.35 days, accounting for 57.7% ~ 92.6% of the patients with no fever after treatment, with an average of 70.3%. Plasmodium was on average about 4 days after treatment