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目的:探讨垂体后叶素治疗剖宫产术中难治性出血的疗效。方法:取2009年3月—2011年11月我院所收行剖宫产术患者170例,随机分为两组,对照组、观察组各85例。观察组:胎儿、胎盘娩出后,予垂体后叶素6U加入生理盐水20ml稀释液,将稀释液局部注射于子宫肌层、缩宫素10U入液静脉点滴、舌下含化米索前列醇200～400ug。对照组:胎儿娩出后,予缩宫素20U子宫肌层注射、缩宫素10U入液静脉点滴、舌下含化米索前列醇200～400ug。观察各组手术平均时间、术中出血量、术后2小时出血量及子宫切除术率。结果:手术平均时间:观察组短于对照组(P<0.05);术中出血量、术后2小时出血量:观察组少于对照组(P<0.05);子宫切除术率:观察组行子宫切除术1例(1.18%),对照组行子宫切除术5例(5.88%)。结论:垂体后叶素对治疗剖宫产术中难治性产后出血患者效果明显,减少了出血量,缩短了手术时间,降低了子宫切除率。
Objective: To investigate the efficacy of pituitrin in the treatment of intractable hemorrhage in cesarean section. Methods: From March 2009 to November 2011, 170 cases of cesarean section received in our hospital were randomly divided into two groups, control group and observation group. Observation group: fetus, placenta after delivery, to the pituitary hormone 6U added 20ml normal saline dilution, the diluent local injection in the myometrium, oxytocin 10U intravenous infusion of sublingual misoprostol 200 ~ 400ug. Control group: After the fetus was delivered to the 20U myometrial oxytocin injection, oxytocin 10U intravenous infusion, sublingual misoprostol 200 ~ 400ug. The mean operation time, intraoperative blood loss, bleeding volume after 2 hours and hysterectomy rate were observed. Results: The mean operative time in the observation group was shorter than that in the control group (P <0.05); the amount of bleeding during operation and the amount of bleeding at 2 hours after operation were lower in the observation group than in the control group (P <0.05); hysterectomy rate Hysterectomy in 1 case (1.18%) and control group in 5 cases (5.88%). Conclusion: Pituitrin is effective in treating refractory postpartum hemorrhage in cesarean section, reducing the amount of bleeding, shortening the operation time and reducing the hysterectomy rate.