原发性颅内淋巴瘤(primary central nervous system lymphoma,PCNSL)是结外非霍奇金淋巴瘤(NHL)的一种少见类型,可侵及脑实质、软脑膜、脉络丛和透明隔等,而无颅外病变。最早由Bailey于1929年报道。与其他大多数颅内肿瘤不同,PCNSL不适于根治性外科切除,甚至局部肿瘤切除术也会对预后造成负面影响,而化疗联合或不联合放疗可明显延长患者生存时间甚至可达到治愈目的。因此,早期准确诊断PCNSL对选择正确的治疗方法和预后尤为重要。 Primary central nervous system lymphoma (PCNSL) is a rare type of extranodal non-Hodgkin’s lymphoma (NHL) that can invade the brain parenchyma, pia mater, choroid plexus, No extracranial lesions. It was first reported by Bailey in 1929. Unlike most other intracranial tumors, PCNSL is not suitable for radical surgical resection and even partial tumor resection can have a negative effect on prognosis. However, chemotherapy combined with or without radiotherapy can significantly prolong the survival time of patients and even achieve the goal of cure. Therefore, the early accurate diagnosis of PCNSL is particularly important for the correct choice of treatment and prognosis.