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目的 运用共焦激光扫描检眼镜(LCSO)测定国人(汉族)视神经乳头(ONH)地形图参数的正常值范围,为临床上青光眼的早期诊断及随访提供依据。方法 用HRT(Heidel-berg Retina Tomograph)技术,检测我国(汉族)74只正常眼ONH地形图参数,经统计学处理,制定各参数的均数(Mean)、标准差(SD)、第5、50、95百分位数(P5、P50、P95)值。并分析ONH参数与种族、性别相关的差异;与年龄、眼别相关的差异作了探讨。结果 国人(汉族)ONH参数的正常值(Meen±SD)为视盘面积(DA)2.34±0.46;视杯面积(CA)0.48±0.28;杯盘面积比(CDR)0.2±0.1;盘沿面积(RA)0.18±0.38;视杯体积(CV)0.1±0.1;盘沿体积(RV)0.5±0.19;平均杯深(MeCD)0.18±0.08;最大杯深(MxCD)0.57±0.21;杯形测量(CSM)-0.25±0.06;曲线高度变化(HVC)0.41±0.12;平均视网膜神经纤维层厚度(mRNFLt)0.27±0.08;视网膜神经纤维层交叉段面积(RNFLcsa)1.47±0.48;标准化参考平面高度(RH)0.29±0.11。各参数P5、P50、P95值分别为DA1、59、2.35、3.05;CA0.11、0.41、0.89;CDR0.06、0.19、0.36;RA1.28、1.82、2.49;CV 0.002、0.06、0.29;RV0.25、0.45、0.84;MeCD 0.05、0.18、0.34;MxCD 0.21、0.59、0.95;CSM-0.35、-0.25、-0.14;HVC 0.23、0.4、0.62;mRNFLt0.14、0.27、0.42;RNF
Objective To determine the normal range of optic nerve head (ONH) topography parameters by confocal laser scanning ophthalmoscope (LCSO) in order to provide the basis for the early diagnosis and follow-up of clinical glaucoma. Methods The parameters of ONH topography of 74 normal eyes of Han nationality in China were detected by HRT (Heidelberg berlin Tomograph) technique. Mean, SD, 50, 95th percentile (P5, P50, P95) value. And analyzed ONH parameters and race, gender-related differences; with age, eye-related differences were discussed. Results The normal (Meen ± SD) of ONH parameters in Chinese were 2.34 ± 0.46 for optic disc area (CA) 0.48 ± 0.28, 0.2 ± 0.1 for cup area ratio (CDR) RA 0.18 ± 0.38; cup volume CV 0.1 ± 0.1; disc rim volume 0.5 ± 0.19; mean cup depth (MeCD) 0.18 ± 0.08; MxCD 0.57 ± 0.21; (CSM) -0.25 ± 0.06; curve height change (HVC) 0.41 ± 0.12; mean retinal nerve fiber layer thickness (mRNFLt) 0.27 ± 0.08; RNFLcsa 1.47 ± 0.48; standardized reference plane height ) 0.29 ± 0.11. Each parameter P5, P50, P95 values were DA1,59,2.35,3.05; CA0.11,0.41,0.89; CDR0.06,0.19,0.36; RA1.28,1.82,2.49; CV 0.002,0.06,0.29; RV0 .25,0.45,0.84; MeCD 0.05,0.18,0.34; MxCD 0.21,0.59,0.95; CSM-0.35, -0.25, -0.14; HVC 0.23,0.4,0.62; mRNFLt 0.14,0.27,0.42; RNF