新生儿多知症(NPCM)累及多器官系统,如脑、心、肺、肾、肠、血液和代谢等,更是儿童时期致残的原因之一。不论因症状确诊的病例,或经实验室筛查发现的病例,通过长期追踪,发现神经系统和发育异常者多达25％。1985年,Black报道,以血浆部分换血治疗本病,神经系统后遗症的发生率从55％降至25％。因此,对本病患者早期诊断、及时治疗的作用是无容置疑的。普遍认为,海拔高,生血旺盛。然而海拔与NPCM的关系却鲜为人知。本文报道海拔为1160m的地区NPCM的发生率。资料与方法 Neonatal polymordity (NPCM) involves multiple organ systems, such as brain, heart, lung, kidney, intestine, blood and metabolism, and is one of the causes of disability during childhood. Up to 25% of the nervous system and dysplasia are found by long-term follow-up, regardless of the number of cases diagnosed or those found in laboratory screening. In 1985, Black reported that transfusion of blood plasma partially reduced the incidence of neurological sequelae from 55% to 25%. Therefore, the early diagnosis of this disease, the role of timely treatment is beyond doubt. Generally believed that high altitude, strong blood. However, the relationship between altitude and NPCM is little known. This article reports the incidence of NPC at an altitude of 1160 m. Materials and Methods