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目的了解葫芦岛市流行性出血热(EHF)的流行特征、变化趋势以及疫区分型,以制订有针对性的防制措施。方法以现场流行病学调查与疫情监测手段,采用间接免疫荧光法检测鼠肺汉坦病毒抗原并计算鼠带毒率,和对EHF恢复期病人血清进行血凝抑制试验(HI)分型。结果有较明显的春季发病高峰,3～6月份发病数占全部发病的49.77%;高发人群为青壮年的男性农民;恢复期病人血清检测推断为家鼠型。结论疫区型别为家鼠型,未向混合型疫区转变。
Objective To understand the epidemiological characteristics and trend of Epidemic Haemorrhagic Fever (EHF) in Huludao City and to establish epidemic prevention and control measures. Methods Epidemiological investigation and epidemic situation monitoring were used in this study. Indirect immunofluorescence assay was used to detect the Hantavirus antigen in rat lung and the virulence rate was calculated. The hemagglutination inhibition test (HI) was performed on patients with EHF convalescent disease. The results showed that the peak incidence in spring was obvious, and the incidence in March to June accounted for 49.77% of the total incidence. The high-incidence population was male farmer in young and middle-aged. The serum level of convalescent patients was inferred as domestic mice. Conclusion The type of epidemic area is a domestic mouse type, and it has not changed to a mixed type epidemic area.