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目的 :研制简易冷冻治疗机并了解该机肝癌切除辅助冷冻治疗的效果。方法 :冷冻机由进气管、容量瓶、输液管、冷冻头构成。用冷冻机对 2 1例主瘤切除 ,余肝或切缘的肝癌残癌进行辅助冷冻 ,冷冻头下方温度 - 80℃～ - 12 0℃ ,冷冻时间 3～ 10min ,重复冷冻 2次。结果 :冷冻区包括全部残癌 ,患者冷冻后均未发生肝破裂出血、胆瘘或腹腔感染等并发症 ,无手术死亡。术后B超、CT示原冷冻区呈坏死后的影像学改变 ,5例肝癌复发再次手术发现原冷冻区呈凝固性坏死 ,无残癌。结论 :此冷冻机可满足肝癌切除辅助冷冻治疗的需要 ,宜推广使用。
OBJECTIVE: To develop a simple cryotherapy machine and understand the effect of adjuvant cryotherapy for liver cancer resection. Methods: freezer from the intake pipe, volumetric flask, infusion tube, frozen head composition. A total of 21 patients with primary tumor resection, residual liver or resected liver cancer were frozen with the freezer. The temperature below the freezing head was between -80 ℃ and -12 0 ℃, and the freezing time was 3 to 10 min. Results: The frozen area consisted of all residual cancer. None of the patients had any complications of hepatic rupture, biliary fistula or abdominal infection after operation. There was no operative death. Postoperative B ultrasound, CT showed the original frozen area was necrotic imaging changes, 5 cases of recurrent liver cancer surgery again found frozen and coagulation necrosis, no residual cancer. Conclusion: This freezer can meet the needs of hepatectomy assisted cryotherapy, should be widely used.