麦克尔细胞又名触觉细胞,是一种胞浆透亮的树枝状突起的细胞,位于表皮基底层。Merkell875年用锇酸染色显示此种细胞与有髓鞘神经纤维的终未突起相联,作为触觉感受器的终末器官(1)。麦克尔细胞的发现距今已有一百多年的历史,但是明确由此种细胞起源而产生的肿瘤却是近几年的事。特别是80年代后,国外皮肤病学者、病理学家应用电镜、免疫化学等手段进行观察,才明确了此类肿瘤的特征。鉴于国内尚无专题报导,特做一综述,以供参考。 Michael cells, also known as tactile cells, are cytoplasmic and transparent dendritic cells located in the basal layer of the epidermis. Merkell’s staining with tannic acid in 875 showed that this kind of cells were associated with the terminal non-projection of myelinated nerve fibers as the terminal organ of tactile receptors (1). The discovery of Michael’s cell has been more than 100 years old, but it is a matter of recent years that it is clear that the tumor originated from this cell origin. Especially after the 1980s, foreign dermatologists and pathologists used electron microscopy and immunochemistry to observe the characteristics of such tumors. In view of the fact that there are no special reports in the country, a special review is provided for reference.