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目的:初步研究早期静脉和动脉内联合应用尿激酶溶栓治疗急性脑梗死(Cerebral infarctrion,CI)的有效性和可行性。方法:对16例病程少于6小时,脑血管造影发现与症状相一致的血管闭塞的脑梗死患者,进行动脉内和静脉内联合溶栓治疗。尿激酶用量不超过100万u。结果:13例血管完全或部分再通,血管再通率为81.25%。基本痊愈6例,显著有效5例,有效3例,总有效率87.5%。并发颅内出血4例,出血转化率25%。结论:静脉和动脉内联合溶栓是一种治疗急性脑梗死安全有效的方法。
OBJECTIVE: To study the efficacy and feasibility of early intravenous and intraarterial combination of urokinase thrombolysis in the treatment of acute cerebral infarction (CI). Methods: Intravenous and intravenous thrombolytic therapy was given to 16 patients with cerebral infarction whose duration of disease was less than 6 hours and whose cerebral angiography was consistent with symptoms. Urokinase dosage does not exceed 1 million u. Results: Thirteen vessels recanalized completely or partially, and the recanalization rate was 81.25%. 6 cases were basically cured, 5 cases were markedly effective, 3 cases were effective, and the total effective rate was 87.5%. 4 cases of intracranial hemorrhage, bleeding conversion rate of 25%. Conclusion: Intravenous and intra-arterial thrombolytic therapy is a safe and effective method for the treatment of acute cerebral infarction.