论文部分内容阅读
rCBF 测定在脑血管病等临床及科研中,具有重要意义,现作一简要综述,供临床应用参考。一、原理:~(133)Xe 是一种具有扩散性,与代谢无关的惰性气体,经吸入到血液后,可迅速透过血脑屏障向脑组织扩散,当停止吸入,它又随血流迅速被清除出来。~(133)Xe 向局部脑组织扩散速度或由局部组织被清除的速度主要取决于流经该局部脑组织血管床的血流量。由于脑各部位血流量不同,~(133)Xe 的放射活性也不同。~(133)Xe 放射活性的变化可通过预先放置在头皮上的探头获取,通过电算机处理,即可得到脑各部位血流量。
rCBF determination in cerebrovascular disease and other clinical and research, of great significance, is a brief review, for clinical application of reference. First, the principle: ~ (133) Xe is a diffusive, and metabolism has nothing to do with the inert gas, after inhalation into the bloodstream, can quickly spread through the blood-brain barrier to the brain tissue, when stopped inhalation, it with blood flow Quickly be cleared out. ~ (133) The rate of diffusion of Xe into or from the local brain depends primarily on the blood flow through the vascular bed of the local brain tissue. Due to the different parts of the brain blood flow, ~ (133) Xe radioactivity is also different. ~ (133) Changes in radiological activity of Xe can be obtained by a probe placed in advance on the scalp. Computerized blood flow can be obtained from all parts of the brain.