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采用放射免疫法对３０例喉鳞状细胞癌病人、２０例声带息肉病人和２０例正常人进行血浆血栓素Ｂ＿２（ＴＸＢ＿２）和６－酮－前列腺素Ｆ＿（１ａ）（６－Ｋｅｔｏ－ＰＧＦ＿（１ａ））测定。结果表明，喉癌病人血浆ＴＸＢ＿２和６－Ｋｅｔｏ－ＰＧＦ＿（１ａ）含量及ＴＸＢ＿２／６－Ｋｅｔｏ－ＰＧＦ＿（１ａ）比值较正常对照组和声带息肉组增高；已发生转移的喉癌病人血浆ＴＸＢ＿２含量较无转移者增高。结果提示血浆ＴＸＢ＿２和６－Ｋｅｔｏ－ＰＧＦ＿（１ａ）含量测定有助于喉癌的辅助诊断，与喉癌的转移可能有关。
Thirty patients with laryngeal squamous cell carcinoma, 20 patients with vocal cord polyp and 20 normal subjects were studied by radioimmunoassay for the determination of TXB_2 and 6-keto-PGF_ (1a) 1a)). The results showed that the levels of TXB_2 and 6-Keto-PGF_1a and the ratio of TXB_2 / 6-Keto-PGF_ (1a) in patients with laryngeal cancer were higher than those in normal controls and vocal cord polyps. Higher than those without transfer. The results suggest that the determination of TXB_2 and 6-Keto-PGF_ (1a) in plasma may be helpful for the auxiliary diagnosis of laryngeal carcinoma, which may be related to the metastasis of laryngeal carcinoma.