子宫颈癌筛查计划降低子宫颈癌的发病率和病死率。子宫颈癌筛查计划中主要针对HPV高危型阳性的早期异型增生性病变,在实际工作中缺乏有效的指标来区分瞬时HPV感染与真正的癌前病变,致使有些患者接受了侵袭性治疗方法如阴道镜检查、活检或锥切,这不仅导致患者治疗费用增高,而且还会造成早产、低出生体重和增加残疾等风险。作者在前瞻性国际多中心收集来自6个中心的908例HIV阴性、非妊娠、未注射HPV-L1疫苗,且诊断为LSIL或中 Cervical cancer screening programs reduce the incidence and mortality of cervical cancer. Cervical cancer screening program mainly for HPV high-risk type of positive early dysplasia, in the actual work of the lack of effective indicators to distinguish between transient HPV infection and true precancerous lesions, resulting in some patients received invasive treatment methods such as Colposcopy, biopsy or conization, which not only lead to increased costs of treatment, but also pose a risk of premature birth, low birth weight and increased disability. The authors collected 908 HIV-negative, non-pregnant, non-HPV-L1 vaccines from 6 centers in a prospective, international multicenter and were diagnosed as LSIL or moderate