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目的 分析婴儿痉挛发作的临床与录像脑电图 (video EEG)特征。方法 对 18例婴儿痉挛发作患儿进行临床观察和录像脑电图监测且回放EEG与录像资料进行同步分析。结果 ①婴儿痉挛发作具有屈曲、伸展及两者混合的多种形式发作 ,痉挛在 1天内可散发或丛集性发作 ,连续性痉挛发作易在入睡或初醒时 ,每 1次连续性痉挛平均发作次数 16回 ,而每日平均发作 6次 ;每回发作持续时间 1～ 3s,间隔时间 5～ 2 0s。②婴儿痉挛发作可与部分性发作或其它形式发作合并出现。③婴儿痉挛EEG特征为背景活动呈高峰节律紊乱 ,发作时呈棘波高波幅慢波爆发 低电压抑制。结论 婴儿痉挛具有独特的发作形式 ,同时又可与部分性发作或其它形式发作合并出现 ,其发作频繁 ,video EEG捕获发作期阳性率高 ,其EEG背景活动及发作期改变均具有特征性。
Objective To analyze the clinical and video EEG features of infantile spasms. Methods 18 cases of infantile spasms in children with clinical observation and video recording EEG monitoring and playback EEG and video data for simultaneous analysis. Results ① Infantile spasms have multiple forms of flexion, extension and combination of both forms of seizures, cramps in 1 day can be distributed or clustered seizures, seizures continuous spasm prone to falling asleep or waking, the average episode of every 1 consecutive spasms The number of 16 times, and the average daily attack six times; each episode duration of 1 ~ 3s, interval 5 ~ 20s. ② Infantile spasms can be combined with partial seizures or other forms of seizures occurred. (3) The characteristics of EEG in infantile spasm showed a rhythm of peak rhythm disorder in the background. At the time of attack, the eEG characteristic of spasm was low voltage suppression of high amplitude slow wave burst. Conclusions Infantile spasms have a unique form of seizures, combined with partial seizures or other forms of seizures. The seizures are frequent and the positive rate of video EEG seizures is high. Both EEG background activity and seizure changes are characteristic.