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目的为了解本地区出生缺陷发生水平和主要缺陷因素,探讨出生缺陷发生的相关因素,为制定干预措施提供依据。方法对2005年10月1日～2010年9月30日象山县所有接生的县、乡镇卫生院里住院分娩孕满28W至产后7天的围产儿进行出生缺陷监测,对其相关因素进行回顾性调查分析。结果 5年间共监测到围产儿34 369例,发生出生缺陷357例,发生率10.39‰。前5位出生缺陷依次为多指(趾)、先心病、总唇裂、先天性脑积水、肾脏畸形。产母年龄35～岁和<20岁两组出生缺陷发生率较高,农村发生率略高于城镇,男性的发生率高于女性。结论降低出生缺陷,预防至关重要,重点推广一级预防,加强二级预防,积极处理三级预防。
Objective To understand the level of birth defects and the main defects in this area, explore the related factors of birth defects and provide the basis for making interventions. Methods From October 1, 2005 to September 30, 2010, all births in Xiangshan County, township hospitals in hospital delivery pregnancy 28W to 7 days postpartum perinatal birth defects monitoring, the relevant factors were retrospectively reviewed research analysis. Results A total of 34 369 cases of perinatal were detected during the 5 years. 357 cases of birth defects occurred, with a prevalence of 10.39 ‰. The first five birth defects followed by multiple fingers (toes), congenital heart disease, total cleft lip, congenital hydrocephalus, kidney malformations. Maternal age 35 ~ and <20 years old, the incidence of birth defects in both groups is higher, the incidence in rural areas slightly higher than the town, the incidence of males is higher than that of females. Conclusions To reduce birth defects, prevention is of the utmost importance. Priority should be given to the promotion of primary prevention, secondary prevention and active prevention of tertiary prevention.