尽管免疫监测在肿瘤发生中的生物学作用尚未确定,但是网状内皮系统一直被认为是宿主对抗肿瘤生长的主要防御机制。一些低等动物如软体动物、棘皮动物以及板鳃亚纲鱼能够产生抗肿瘤物质。业已证实这些物质对网状内皮系统有刺激作用。作者用葡聚糖凝胶柱层析从鲟(Sturgeon)血清中分离到A、B、C 三种抗肿瘤物质。这三种组分对人类肿瘤细胞有杀伤作用而对正 Although the biological role of immune surveillance in tumorigenesis has not been established, reticuloendothelial system has been considered as the main defense mechanism of host against tumor growth. Some lower animals such as mollusks, echinoderms, and subchondria can produce anti-tumor substances. It has been confirmed that these substances have a stimulatory effect on the reticuloendothelial system. The authors isolated three anti-tumor substances A, B, and C from Sturgeon serum using Sephadex gel column chromatography. These three components have a killing effect on human tumor cells and are positive