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目的探讨不同雾化吸入方式对老年慢性阻塞性肺病急性加重期的治疗效果差异。方法选择我院近年来诊治的慢性阻塞性肺病老年患者共100例,上述患者随机分为观察组和对照组。两组患者均给予抗生素抗感染、镇咳祛痰、糖皮质激素类药物、吸氧等治疗。观察组采用湿化瓶氧气雾化吸入,对照组采用经空气压缩雾化吸入。两组患者均吸入异丙托溴铵和硫酸沙丁胺醇。治疗期间观察两组患咳嗽、咳痰、发绀、呼吸困难、哮鸣音等临床症状和体征的改善情况,对两组患者定期进行血气分析,检测肺功能。结果观察组总有效率为96.0%,对照组总有效率为78.0%,观察组总有效率显著高于对照组,差异有统计学意义(P<0.05)。结论经湿化氧气雾化双鼻导管吸入治疗慢性阻塞性肺病急性加重期临床效果显著,优于空气压缩雾化吸入,值得借鉴。
Objective To explore the difference of the therapeutic effect of different inhalation modes on senile chronic obstructive pulmonary disease (AOPP) in acute exacerbation. Methods A total of 100 elderly patients with COPD who were diagnosed and treated in our hospital in recent years were randomly divided into observation group and control group. Two groups of patients were given anti-infective antibiotics, antitussive expectorant, glucocorticoid drugs, oxygen and other treatment. The observation group was aerosolized with humidified bottle, while the control group was inhaled by air compression. Both groups inhaled ipratropium bromide and salbutamol sulfate. The two groups were observed during the treatment of cough, sputum, cyanosis, dyspnea, wheeze and other clinical symptoms and signs of improvement, two groups of patients on a regular basis blood gas analysis, detection of lung function. Results The total effective rate was 96.0% in the observation group and 78.0% in the control group. The total effective rate in the observation group was significantly higher than that in the control group (P <0.05). Conclusion The humidified oxygen atomized double nasal cannula inhalation for the treatment of chronic obstructive pulmonary disease in acute exacerbation clinical effect is better than air compression inhalation is worth learning.