王某,女,70岁。因咽痛于1988年9月2日在当地卫生所注射青霉素80万单位,注后患者皮肤潮红,出现丘疹样荨麻疹,诊断为“青霉素过敏反应”,即注射肾上腺素1毫克,30分钟后皮肤潮红和荨麻疹消退,但四肢宋端青紫、疼痛,以左手指明显。应用酚妥拉明、普鲁卡因交替封闭指、趾端,右上肢及双下肢症状消失,但左手指端皮肤发黑,疼痛加重,于 Wang, female, 70 years old. Due to sore throat on September 2, 1988 at the local health office injections of penicillin 800,000 units, the patient’s skin flushing note, there papular urticaria, diagnosed as “penicillin allergic reaction”, that is, injection of 1 mg of epinephrine, 30 minutes later Skin flushing and hives subsided, but the limbs Song bruising, pain, obvious to the left hand. Application of phentolamine, procaine alternately closed refers to the toe, right upper limb and lower extremity symptoms disappear, but the left finger end of the skin blackening, increased pain in