论文部分内容阅读
目的探讨胺碘酮小剂量治疗室性早搏保持疗效、降低副作用的可行性。方法选择门诊有自觉症状无器质性心脏病的室性早搏患者,口服胺碘酮0.2 g,每天3次,3 d后治疗有效者随机分为治疗组58例,观察组58例。治疗组口服胺碘酮维持量根据个体情况逐渐减至0.025～0.05 g/d,观察组口服胺碘酮维持量0.2 g/d。维持治疗第1、2周、第1、2、3个月,分别来门诊复诊1次。结果治疗组、观察组有效率分别为91%和95%(P>0.05),不良反应发生率分别为5%和22%(P<0.01)。结论胺碘酮小剂量治疗室性早搏有效更安全。
Objective To investigate the feasibility of low dose amiodarone treatment of ventricular premature beats to maintain efficacy and reduce side effects. Methods Outpatients with ventricular premature beats without symptoms of organic heart disease were randomly divided into treatment group (58 cases) and observation group (30 cases). The patients were treated with amiodarone 0.2 g orally three times a day. The treatment group oral amiodarone maintenance dose gradually reduced to 0.025 ~ 0.05 g / d, the observation group oral amiodarone maintenance 0.2 g / d. The first and second week of maintenance treatment, first, second and third months, respectively, outpatient referral 1 time. Results The effective rates of the treatment group and the observation group were 91% and 95%, respectively (P> 0.05), and the adverse reactions were 5% and 22% respectively (P <0.01). Conclusion Amiodarone small dose of ventricular premature beats effective and safer.