目的:观察去氧孕烯炔雌醇片提高药物流产成功率的临床疗效。方法:68例接受药物流产的早期妊娠患者随机分为观察组和对照组。两组患者均常规予米非司酮配伍米索前列醇终止妊娠,观察组在此基础上加用去氧孕烯炔雌醇片1片,qd,连用21d。比较两组药物流产成功率、阴道出血时间和阴道出血量、月经恢复情况及并发症的发生率。结果:观察组药物流产成功率及完全流产成功率均高于对照组(P<0.05),阴道出血时间、流产后月经恢复时间短于对照组(P<0.05),阴道出血量明显少于对照组(P<0.01),流产后并发症发生率低于对照组(P<0.05)。两组患者治疗期间均未发生严重药品不良反应。结论:药物流产后口服去氧孕烯炔雌醇片可提高药物流产的成功率,缩短阴道出血时间,减少阴道出血量,有利于月经恢复,减少并发症,安全性好。 Objective: To observe the clinical efficacy of ethinyl ethinyl estradiol in improving the success rate of medical abortion. Methods: Sixty-eight patients with early pregnancy receiving medical abortion were randomly divided into observation group and control group. Two groups of patients were routinely given mifepristone with misoprostol termination of pregnancy, the observation group on this basis plus degestin ethinyl estradiol tablets 1, qd, once every 21d. The success rate of medical abortion, vaginal bleeding time and vaginal bleeding, menstrual recovery and the incidence of complications were compared between the two groups. Results: The success rate of medical abortion and the success rate of complete abortion in observation group were higher than those in control group (P <0.05). Vaginal bleeding time, menstruation recovery time after abortion were shorter than those in control group (P <0.05) Group (P <0.01). The incidence of complications after abortion was lower than that of control group (P <0.05). Two groups of patients during treatment did not occur serious adverse drug reactions. Conclusion: After the medical abortion, oral administration of desogestrel ethinyl estradiol tablets can improve the success rate of medical abortion, shorten the time of vaginal bleeding, reduce the amount of vaginal bleeding, facilitate the recovery of menstruation, reduce the complications and have good safety.