Searchde novo protein designon Google and you will find the name David Baker in all results of the first page.Professor David Baker at the University of Washington and other scientists are opening up a new world of fantastic proteins.Protein is the direct executor of most biological functions and its structure and function are fully determined by its primary sequence.Bakers group developed the Rosetta software suite that enabled the computational prediction and design of protein structures.Being able to design proteins from scratch means being able to design executors for diverse purposes and benefit society in multiple ways.Recently, NSR interviewed Prof.Baker on this fast-developing field and his personal experiences.