论文部分内容阅读
急性呼吸道感染(ARTIs)是人类健康的主要威胁,据统计每年有400万儿童死于各类呼吸道感染导致的肺炎。90%以上的ARTIs是由病毒引起,但仍有大约30%的ARTIs病原不能确定。WU多瘤病毒于2007年由美国学者Gay-nor等通过高通量序列测定从肺炎患者的呼吸道标本中发现,但是否为呼吸道致病原还存在争议。目前的研究热点多集中在WU多瘤病毒的致病性和流行病学特点方面。该病毒属于多瘤病毒科多瘤病毒属,生物学性状与该属病毒相似。该病毒多在儿童标本中检出,其季节分布稍有差异。WU多瘤病毒与其他呼吸道病毒混合感染常见,故是否为一种独立的致病原还需进一步研究。目前的研究方法多采用PCR和荧光定量PCR扩增技术。
ARTIs are a major threat to human health and it is estimated that 4 million children die of pneumonia each year due to various types of respiratory infections. More than 90% of ARTIs are caused by viruses, but about 30% of ARTIs are still undetermined. WU polyoma virus was discovered in respiratory samples from patients with pneumonia by high-throughput sequencing by American scholar Gay-nor et al in 2007. However, whether or not it is a respiratory pathogen is still controversial. The current research focus more on the pathogenic and epidemiological characteristics of WU polyoma virus. The virus belongs to the genus Polyomavirus, the biological trait is similar to the genus. The virus is mostly detected in children’s specimens, the seasonal distribution of a slight difference. WU polyoma virus mixed with other respiratory viruses common, so whether it is an independent cause of pathogenesis needs further study. The current research methods and more use of PCR and fluorescence quantitative PCR amplification technology.