脑胶质瘤占颅内肿瘤的４０％～５０％。一般而言，平均生存期不超过１年。现有的治疗措施如外科手术切除、术后放疗、化疗和免疫治疗难以达到根除，复发率很高，严重影响生存质量和生存期。９０年代由于肿瘤分子生物学理论与技术的发展，使得基因治疗成为医学研究领域的前... Gliomas account for 40% to 50% of intracranial tumors. In general, the average survival period does not exceed 1 year. Existing treatment measures such as surgical resection, postoperative radiotherapy, chemotherapy and immunotherapy are difficult to achieve eradication, and the recurrence rate is high, which seriously affects the quality of life and survival. In the 1990s, due to the development of the theory and technology of tumor molecular biology, gene therapy became the predecessor of medical research...