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目的 研究肝素、纳洛酮及氨溴索联合应用治疗肺性脑病的疗效。方法 将 90例肺性脑病病人随机分为三组。A组 30例采用常规方法治疗 ;B组 30例常规方法 +肝素 ;C组 30例常规方法 +肝素 +纳洛酮 +氨溴索。三组疗程均为 1周 ,并观察其疗效及血气分析变化。结果 A、B、C三组总有效率分别为6 0 %、83 3%、96 7% ,B组、C组与A组疗效比较差异有显著意义 (P <0 0 5 ,P <0 0 1)。结论 加用肝素、纳洛酮及氨溴索联合治疗肺性脑病疗效显著 ,可迅速改善临床症状 ,使用安全 ,不良反应少 ,值得临床推广应用。
Objective To study the curative effect of heparin, naloxone and ambroxol on pulmonary encephalopathy. Methods Ninety patients with pulmonary encephalopathy were randomly divided into three groups. 30 cases in group A were treated by conventional method; 30 cases in group B were treated by conventional method and heparin; in group C, 30 cases were treated by heparin + naloxone + ambroxol. The three groups were treated for 1 week, and observed its efficacy and blood gas analysis changes. Results The total effective rates of groups A, B and C were 60%, 83 3% and 96 7% respectively. There was significant difference between group B, C and group A (P <0.05, P <0 0 1). Conclusion Heparin, naloxone and ambroxol combined treatment of pulmonary encephalopathy significant effect, can quickly improve clinical symptoms, safe, less adverse reactions, it is worthy of clinical application.