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甲硝乙基磺酰咪唑(Tinidazole)是一种新型咪唑类衍生物,为抗原虫的新药,可用于治疗阴道毛滴虫,贾弟氏鞭毛虫和溶组织肠阿米巴等原虫感染。作者研究其对肝脏阿米巴病的疗效。接受治疗的20例阿米巴肝病患者,男性16例,女性4例,年龄为22～60岁。甲硝乙基磺酰咪唑用量为每次口服500毫克,1天3次,连服5天。结果与副作用:20例患者治疗前发热者12例。服药第2天退热者3例,第3天退热者6例,第4天退热者2例,于第5天所有病例发热均消退,此后随访期内未见复发。20例患者均有不同程度的肝脏疼痛与肿大,
Tinidazole is a novel imidazole derivative that is a new drug against protozoa that can be used to treat protozoal infections such as Trichomonas vaginalis, Giardia lamblia, and E. histolytica. The authors studied its efficacy on hepatic amoebiasis. Twenty patients with amoebic liver disease were treated, 16 males and 4 females, aged 22-60 years. Metronidazole ethyl sulfonyl imidazole dosage for each oral 500 mg, 3 times a day, even for 5 days. Results and side effects: 20 patients before treatment, 12 cases of fever. 3 cases of fever on day 2, 6 cases of fever on day 3, and 2 cases of fever on day 4. All cases were subsided on day 5, and no recurrence was found during the follow-up period. 20 patients had varying degrees of liver pain and swelling,