口服丙磺舒引起恶性大疱性多形红斑样发疹尚未见报告,现报告一例如下。韦某,男性,52岁,1986年3月23日以痛风诊断入院。患者主诉四肢关节肿痛,运动受限,发热(38.5℃)。给予秋水仙素、青霉素等治疗,两周后,体温渐趋平复,关节痛亦见减轻,血尿酸下降。但病情恢复缓慢,于4月7日起加服丙磺舒和消炎痛等,关节痛消失。于服用丙磺舒 Oral probenecid-induced malignant bullous erythema multiforme-like rash has not been reported, a report is as follows. Wei Mou, male, 52 years old, March 23, 1986 with gout diagnosis and admission. Patients complained of swollen joints, limited movement, fever (38.5 ℃). Give colchicine, penicillin and other treatment, two weeks later, the body temperature gradually recovered, joint pain also see relief, decreased blood uric acid. However, the condition recovered slowly, since April 7 plus probenecid and indomethacin, arthralgia disappeared. In the use of probenecid