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庆大霉素的肾毒性作用日益为临床医师所重视,导致急性肾功能衰竭(ARF)的报告已占ARF 之5～22%但庆大霉素仍不失为治疗革兰氏阴性杆菌感染的有效抗生素。因此如何合理用药,早期发现肾毒性作用,防治ARF 是当前临床医师所关心的问题.现将我们对短期应用庆大霉素患儿的尿N-乙酰-β-氨基葡萄糖酶(NAG)测定结果报告分析如下.
Genetically toxic effects of gentamicin are increasingly valued by clinicians and reports of acute renal failure (ARF) have accounted for 5-22% of ARF, but gentamicin remains an effective antibiotic for the treatment of gram-negative bacilli . Therefore, how to use medicine rationally, early detection of nephrotoxic effect and prevention and treatment of ARF are the concerns of current clinicians.We will now analyze the results of urine N-acetyl-β-glucosaminidase (NAG) assay in short-term use of gentamicin in children The report is analyzed as follows.