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目的探讨腹腔镜手术联合应用药物治疗中重度子宫内膜异位症并发不孕的临床疗效。方法回顾性分析许昌市公疗医院2009年6月至2011年6月收治的68例腹腔镜手术联合药物治疗的中重度子宫内膜异位合并不孕症患者诊疗资料,同单纯采用手术治疗的同期患者68例进行比较。两组患者在6、12、18、24个月复发率和妊娠率以及两组患者术后腹痛、性交痛发生率。结果观察组患者术后6、12、18、24个月复发率分别为8.82%、11.76%、17.65%、22.06%,明显低于对照组,组间比较差异具有统计学意义(P<0.05)。术后6、12、18、24个月妊娠率32.35%、39.71%、44.93%、57.35%,明显高于对照组,组间比较差异具有统计学意义(P<0.05)。结论在手术治疗的基础上联合应用药物治疗中重度子宫内膜异位症并发不孕症,可有效提高疗效,降低临床复发,提高妊娠率。
Objective To investigate the clinical efficacy of laparoscopic surgery combined with drugs in the treatment of moderate-severe endometriosis complicated with infertility. Methods The clinical data of 68 patients with moderate-severe endometriosis complicated with infertility treated by 68 laparoscopic surgery combined with drug in Xuchang Public Hospital from June 2009 to June 2011 were retrospectively analyzed. The data of surgical treatment 68 patients were compared over the same period. The recurrence rate and pregnancy rate of the two groups at 6, 12, 18, 24 months and the incidence of postoperative abdominal pain and painful intercourse were compared between the two groups. Results The recurrence rates of observation group were 8.82%, 11.76%, 17.65% and 22.06% respectively at 6, 12, 18 and 24 months after operation, which were significantly lower than those in control group (P <0.05) . The pregnancy rates at 6, 12, 18 and 24 months after operation were 32.35%, 39.71%, 44.93% and 57.35%, respectively, which were significantly higher than those in the control group (P <0.05). Conclusion In combination with surgical treatment of medications based on the treatment of moderate and severe endometriosis complicated by infertility, which can effectively improve the efficacy, reduce clinical recurrence, improve pregnancy rate.