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Schumanniofoside(简称Sche),是茜草科植物Schumanniophyton magnificum 茎叶提取物,在非洲最常用于治疗蛇咬伤。其石油醚、氯仿、乙醇和水的提取物对预防小鼠黑眼镜蛇毒中毒无效;而甲醇提取物和将甲醇提取物反复用硅胶层析以及用不同比例的氯仿-甲醇混合物洗提,所得Sche 有明显的预防小鼠蛇毒中毒怍用。Sche 对小鼠的LD_(50)为2.88g/kg.经光谱数据和化学反应确定其化学结构如下:
Schumanniofoside (Sche), a Schumanniophyton magnificum stem and leaf extract of Rubiaceae, is most commonly used to treat snake bites in Africa. The petroleum ether, chloroform, ethanol and water extracts of mice to prevent black cobra venom poisoning ineffective; and methanol extract and the methanol extract repeatedly with silica gel chromatography and with different proportions of chloroform - methanol mixture of the Sche There is a clear prevention of mouse snake venom poisoning use. Schem LD_ (50) of mice was 2.88g / kg.The chemical structure was determined by spectroscopic data and chemical reaction as follows: