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自1961年首次报道红细胞丙酮酸激酶(PK)缺乏以来,迄今已发现急性白血病、慢性粒细胞白血病、恶性淋巴瘤和骨髓异常增生综合征等多种血液病可具有获得性PK缺乏。本文首次报道红细胞PK缺乏症发生急性粒细胞白血病。
Various blood diseases such as acute leukemia, chronic myeloid leukemia, malignant lymphoma and myelodysplastic syndrome have hitherto been found to have acquired PK deficiency so far since the first report of erythrocyte pyruvate kinase (PK) deficiency in 1961. This article first reported erythrocyte PK deficiency in acute myeloid leukemia.