论文部分内容阅读
目的分析妊娠期糖尿病(gestational diabetes mellitus,GDM)及孕母胰岛素应用与新生儿低血糖发生的相关性。方法选取2010年6月至2013年12月东莞市妇幼保健院GDM产妇分娩的新生儿82例作为研究组,同期糖耐量正常的产妇分娩的新生儿50例作为对照组。研究组分为研究组A(未应用胰岛素者,42例)和研究组B(应用胰岛素者,40例)。在新生儿出生后0.5 h、2 h、6 h、12 h、24 h取足后跟血进行微量血糖测定,并比较3组结果。结果研究组A发生低血糖症5例(11.90%),其中2例(4.76%)为巨大儿;研究组B发生低血糖症4例(10.0%),其中2例(5.0%)为巨大儿;对照组未出现低血糖症新生儿和巨大儿;3组比较差异有统计学意义(P<0.05);出生后0.5 h时对照组血糖值[(3.91±0.52)mmol/L]高于研究组A[(3.42±0.61)mmol/L]、研究组B[(3.41±0.62)mmol/L](P<0.05);出生后2 h、6 h、12 h、24 h 4个时间点3组新生儿血糖值差异均无统计学意义(P>0.05)。结论 GDM及胰岛素应用的产妇分娩的新生儿尤其是巨大儿易发生低血糖症。
Objective To analyze the correlation between gestational diabetes mellitus (GDM) and gestational insulin and hypoglycemia in neonates. Methods From June 2010 to December 2013, 82 newborns with GDM maternal delivery in Dongguan Maternal and Child Health Care Hospital were selected as the research group. Fifty newborns with normal glucose tolerance during the same period were selected as the control group. The study group consisted of study group A (42 without insulin) and study group B (40 with insulin). Blood samples were taken at 0.5 h, 2 h, 6 h, 12 h and 24 h after birth, and blood glucose was measured. The results of three groups were compared. Results There were 5 cases (11.90%) of hypoglycemia in study group A, 2 cases (4.76%) were giant ones, and 4 cases (10.0%) of hypoglycemia in study group B. 2 cases (5.0% (P <0.05). The blood glucose level of control group [(3.91 ± 0.52) mmol / L] at 0.5 h after birth was higher than that of the study Group A [(3.42 ± 0.61) mmol / L], B [(3.41 ± 0.62) mmol / L] in study group (P <0.05) There was no significant difference in neonatal blood glucose between the two groups (P> 0.05). Conclusions GDM and insulin-producing mothers are particularly vulnerable to hypoglycemia in newborns.