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目的探讨贲门癌行全胃切除手术的临床治疗效果。方法选取2011年1月至2012年12月收治的贲门癌患者86例为研究对象,根据患者病情分为全胃切除组46例(观察组)及行胃大部分切除术组40例(对照组),对两组患者的临床资料进行回顾性分析,并于术后分别对两组患者进行1、3、5年的随访。结果观察组患者治疗后1年生存率与对照组比较差异无统计学意义(P>0.05),但复发率显著低于对照组(P<0.05),治疗后第3年、第5年,观察组的生存率显著优于对照组(P<0.05),复发率显著低于对照组(P<0.05)。结论对贲门癌患者行全胃手术切除治疗能有效提高患者治疗效果,不会增加患者的病死率及并发症发生率,能有效提高患者的远期生存率。
Objective To investigate the clinical effect of total gastrectomy for cardia cancer. Methods Eighty-six patients with cardia cancer who were admitted from January 2011 to December 2012 were selected as the study subjects. According to the patients’ condition, they were divided into total gastrectomy group (46 cases) and gastric gastrectomy group (40 cases) ), The clinical data of two groups were retrospectively analyzed, and were followed up for 1, 3 and 5 years respectively. Results The 1-year survival rate of the observation group was not significantly different from that of the control group (P> 0.05), but the recurrence rate was significantly lower in the observation group than in the control group (P <0.05). After the third and fifth years of treatment, Group survival rate was significantly better than the control group (P <0.05), the recurrence rate was significantly lower than the control group (P <0.05). Conclusions The total gastric resection for cardia cancer patients can effectively improve the therapeutic effect of patients without increasing the mortality and complication rate of patients, which can effectively improve the long-term survival rate of patients.