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该院口腔厌氧菌室在“全军八五规划医药卫生科研基金”资助下,根据龈下菌斑关键性厌氧菌具有胰蛋白酶样活性,可使人工合成的苯甲酰精氨酸萘酰胺(BANA)水解的原理,研制出了BANA检测试剂,为牙周病辅助诊断提供了新的方法。 龈下菌斑中的牙龈卟啉杆菌、齿密螺旋体、嗜二氧化碳噬纤维菌、Bacteroides forsythus等均为活动性牙周病变的关键性病原。临床对其检测的方法目前多为分离培养法。BANA检测试剂的特点是,1.不需特殊设备与试剂,操作简单,易掌握;2.可使分离培养法鉴定周期由至少需要2周的时间,缩短到只需18小时,适合在临床广泛应用;3.敏感性
The hospital oral anaerobic bacteria room in the “Eight Five-Year Plan medical and health research fund” funded, according to the key anaerobic subgingival plaque with trypsin-like activity, can make synthetic benzoyl arginine naphthalene Amide (BANA) hydrolysis principle, developed a BANA test reagent, which provides a new method for the diagnosis of periodontal disease. Porphyromonas gingivalis, Treponema pallidum, Bacteroides forsythus and other bacteria in subgingival plaque are the key pathogens of active periodontal disease. Clinical testing methods for the current separation culture method. BANA test reagent is characterized by 1. without special equipment and reagents, easy to operate, easy to grasp; 2. separation culture can be identified by the cycle of at least 2 weeks, shortened to only 18 hours, suitable for a wide range of clinical Application; 3. Sensitivity