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目的:观察胞二磷胆碱与复方丹参注射液治疗新生儿缺氧缺血性脑病的临床效果。方法:选择在我院住院的缺氧缺血性脑病新生儿患儿共70例,随机分为观察组和对照组各35例,两组患儿均给予供氧、控制惊厥、治疗脑水肿、限制入液量和对症支持等常规治疗。对照组给予单一注射神经生长因子;观察组给予胞二磷胆碱与复方丹参注射液治疗。结果:观察组总有效率明显优于对照组,差异有统计学意义(P<0.05)。结论:常规治疗基础上加用胞二磷胆碱与复方丹参注射液治疗新生儿缺氧缺血性脑病疗效满意,值得推广。
Objective: To observe the clinical effect of citicoline and compound Danshen injection in treating neonatal hypoxic-ischemic encephalopathy. Methods: A total of 70 neonates with hypoxic-ischemic encephalopathy hospitalized in our hospital were randomly divided into observation group (35 cases) and control group (35 cases). Both groups were given oxygen and control seizures to treat cerebral edema, Limit fluid intake and symptomatic support and other routine treatment. Control group given a single injection of nerve growth factor; observation group given citicoline and compound Salvia injection treatment. Results: The total effective rate in observation group was significantly better than that in control group, the difference was statistically significant (P <0.05). Conclusion: The addition of citicoline and compound Danshen injection to neonatal hypoxic-ischemic encephalopathy based on routine treatment is satisfactory and worthy of promotion.