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目的:探讨高原地区低钾性周期性麻痹(hypokalemic preiodic parlysis,HOPP)的诱发因素、临床表现及诊治体会。方法:分析我院2003年1月—2007年12月收治170例HOPP患者的临床资料。结果:高原低氧环境及上呼吸道感染为主要原因,最早表现为四肢不同程度的迟缓性肌无力;全部病例经静脉及口服补钾等治疗后症状完全缓解。结论:对于HOPP及早诊治是关键;而对于重度HOPP,心电监护、抗心律失常药物和呼吸机辅助呼吸是抢救成功的重要措施。
Objective: To investigate the predisposing factors, clinical manifestations and diagnosis and treatment of hypokalemic preiodic parlysis (HOPP) in the plateau. Methods: The clinical data of 170 HOPP patients admitted to our hospital from January 2003 to December 2007 were analyzed. Results: The plateau hypoxia environment and upper respiratory tract infection were the main causes. The earliest manifestations were delayed myasthenia gravis with different degrees of limbs. The symptoms were completely relieved after intravenous and oral potassium treatment in all cases. Conclusions: Early diagnosis and treatment of HOPP is the key. Severe HOPP, ECG monitoring, anti-arrhythmic drugs and ventilator-assisted breathing are important measures for successful rescue.