脾脏在防御急性疟疾感染中起着关键性作用,特别是在致死性恶性疟感染中,脾脏具有吞噬寄生和非寄生红细胞的能力。通过其巨噬细胞上的受体可清除免疫球蛋白所包被的颗粒性物质,对IgG包被红细胞的清除作用取决于结合到红细胞上的IgG分子数目、抗体激活补体的能力和脾Fc受体的活性。为了测定急性恶性疟病人中脾Fc受体的功 The spleen plays a key role in the defense of acute malaria infections, especially in the case of lethal falciparum malaria infection, where the spleen has the ability to engulf parasitic and non-parasitic erythrocytes. Removal of immunoglobulin-coated particulate matter by its receptors on macrophages depends on the number of IgG molecules bound to erythrocytes, the ability of the antibody to activate complement, and the splenic Fc receptor Body activity. To determine the work of splenic Fc receptors in patients with acute falciparum malaria