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Background:GBS, demyelinating disease,which was common in peripheral nerve system and may be resulted from abnormal autoimmunity.In recent years,GBS complicated with impairment of central nerve system has been paid close attention.MRI,electrically physiological examination and biopsy of peripheral nerves all confirmed the coexistence of GBS and impaired central nerve system.Objective:To analyze the characteristics of dysfunction of patients with variant GBS.Unit: Nervous Intal Medicine Deparetment of Peoples Hospital of Yansan County of Hebei.