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目的:探讨分析院前急救措施对急性有机磷农药中毒的急救效果。方法:随机选取2012年8月至2016年8月广东省水电医院收治的急性有机磷农药中毒患者120例,按照是否采取了院前急救措施分为观察组和对照组,各60例,回顾分析两组患者临床资料,包括从中毒到开始实施急救时间、从中毒到开始洗胃时间、阿托品总用量、患者出现阿托品化所需时间、入院前患者死亡率、总死亡率、解磷定总用量、胆碱酯酶活性恢复到标准值的1/2所需时间以及住院天数等指标。结果:观察组患者从中毒到开始实施急救时间和从中毒到开始洗胃时间明显短于对照组患者,观察组患者的入院前患者死亡率和总死亡率均低于对照组患者。观察组患者出现阿托品化所需时间和胆碱酯酶活性恢复到标准值的1/2所需时间均短于对照组,阿托品总用量和解磷定总用量均少于对照组,住院天数短于对照组,两组患者各项指标比较,差异均具有统计学意义(P<0.05)。结论:院前急救措施对急性有机磷农药中毒的效果显著,可明显降低患者的死亡率,缩短住院天数。
Objective: To investigate the first aid effect of prehospital emergency measures on acute organophosphorus pesticide poisoning. Methods: A total of 120 patients with acute organophosphorus pesticide poisoning admitted to Guangdong Provincial Hydropower Hospital from August 2012 to August 2016 were randomly selected and divided into observation group and control group according to whether pre-hospital emergency measures were taken or not, 60 cases each. The retrospective analysis The clinical data of the two groups included the time from poisoning to starting the first aid, the time from poisoning to starting the gastric lavage, the total amount of atropine used, the time required for atropine in the patient, the patient mortality before admission, the total mortality, the total phosphate dose , Cholinesterase activity restored to the standard value of 1/2 time required, as well as hospital days and other indicators. Results: The observation group patients from the poisoning to the beginning of the implementation of the first aid time and starting from the poisoning to gastric lavage time was significantly shorter than the control group, the observation group patients pre-hospital mortality and total mortality were lower than the control group. The time required for atropisation and recovery of cholinesterase activity to 1/2 of the standard value in the observation group were shorter than those in the control group. The total amount of atropine and total phosphorus release was less than that of the control group, and the length of hospital stay was shorter The control group, the two groups of patients with various indicators, the differences were statistically significant (P <0.05). Conclusion: Prehospital emergency measures have significant effect on acute organophosphorus pesticide poisoning, which can significantly reduce the mortality rate and shorten the length of hospital stay.