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目的 探讨囊性颅咽管瘤胶体磷酸铬(Cr3 2 PO4)囊腔内放疗的有效性和安全性。方法 对9例囊性颅咽管瘤行3 2 P囊腔内放疗,根据个体化剂量设计分别置入1.5～5 .0mCi不等3 2 P并进行临床观察、随访。结果 9例病人术后神经功能均有不同程度改善。随访6～30个月,8例视力、视野明显改善;1例右眼视力改善,左眼术前失明,术后无变化;5例囊腔缩小>5 0 % ,2例缩小<5 0 % ,2例囊腔复发再次穿刺抽液;无手术死亡及严重并发症。结论 3 2 P囊腔内放疗是治疗囊性颅咽管瘤有效且安全的方法。
Objective To investigate the efficacy and safety of colloidal chromium (Cr3 2 PO4) encapsulation in cystic craniopharyngioma. Methods 9 cases of cystic craniopharyngioma were treated with 3 2 P intracavitary radiotherapy. According to the individual dose design, 1.5 ~ 5.0mCi ranged from 3 to 2 P respectively. The clinical observation and follow-up were performed. Results Nine patients had different degrees of postoperative neurological function improvement. After 6 months to 30 months of follow-up, visual acuity and visual field of 8 cases were significantly improved. One case had visual acuity of the right eye and left blind before operation, no change after operation; 5 cases of cyst shrinkage> 50%, 2 cases of <50% , 2 cases of cyst recurrence again puncture fluid; no surgical death and serious complications. Conclusion 3 2 P cavity intracavitary radiotherapy is an effective and safe treatment of cystic craniopharyngioma.