论文部分内容阅读
首先对3种保护剂冻干的麻疹乙脑二联苗进行滴度比较，结果3种保护剂的二联疫苗中麻疹病毒滴度差异均无显著意义；而对乙脑病毒滴度显示出保护剂Ⅱ和Ⅲ明显优于Ⅰ。选择保护剂Ⅲ制备二联苗和单价苗进行热稳定性试验，其中麻疹病毒在37℃对天及50℃72h的滴度下降均＜1．0Log。乙脑病毒在37℃14天及在50℃24h滴度下降均＜1．0Log。表明保护剂Ⅲ对麻疹沪191株和乙脑14－2株病毒的热保护作用均好。
First of all three kinds of protective agent lyophilized measles JE vaccine titers comparison, the results of the three protective agents in the two vaccines measles virus titer was no significant difference; while the JE virus titer showed protection Agents Ⅱ and Ⅲ were significantly better than Ⅰ. The protective agent Ⅲ was used to prepare the thermo-stability test of the two-spike and monovalent seedlings. The measles virus titer decreased to <1.0Log at 37 ℃ and 72 ℃ at 50 ℃ respectively. JE virus titres were all <1.0 log at 37 ° C for 14 days and at 50 ° C for 24 h. The results showed that the protective effect of the protectant III on the heat-sensitive effects of measles strain 191 and JE strain 14-2 were good.