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为了探讨低浓度锰对电焊作业者神经行为功能的影响,进而为慢性锰中毒的早期诊断以及现行锰的卫生标准的安全性评价提供科学依据,本文采用WHO推荐的“神经行为核心测验组合”(NCTB)对69名电焊工人及其对照组进行了神经行为功能测定。结果,电焊工人由于长期暴露于低浓度锰(0.0093～0.1559mg/m~3),即使在临床体检正常的情况下,情绪状况特征和神经行为功能已出现了改变。经逐步回归分析,累积接触量与紧张焦虑、愤怒敌意、有力好动,手运动速度及视感知记忆之间具有非常显著相关性(R=0.596181,P<0.01);结果表明,行为功能测定在慢性锰中毒早期诊断方面可提供定量的评价指标;我国现行车间空气中锰的最高容许浓度(0.2mg/m~3)的安全性似有待进一步研究和修订。
In order to explore the effect of low concentration of manganese on the neurobehavioral function of electricians, and then to provide a scientific basis for the early diagnosis of chronic manganese poisoning and the safety evaluation of the current health standards of manganese, this paper adopts the “core behavioral core test” NCTB) performed neurobehavioral functional tests on 69 welders and their controls. As a result, the long-term exposure of welders to low concentrations of manganese (0.0093 ~ 0.1559mg / m ~ 3), even in the case of normal clinical examination, emotional status and neurobehavioral features have changed. Through stepwise regression analysis, there was a significant correlation between accumulated exposure and anxiety, anger, hostility, hand movement speed and visual memory (R = 0.596181, P <0.01). The results showed that behavioral function was positively correlated with Chronic manganese poisoning early diagnosis can provide quantitative evaluation indicators; China’s current workshop air manganese maximum allowable concentration (0.2mg / m ~ 3) security needs further study and revision.